Rodolphe is focusing on the characterization of CRISPR-Cas systems, and their applications in bacteria. The CRISPRlab has published numerous studies on the application of CRISPR-Cas systems, and illustrated their use for the study and development of probiotics, including for genotyping, phage resistance, and genome editing to understand and enhance health-promoting functions of interest.
The work includes developing and applying novel technologies to develop and formulate next-generation probiotic strains. Rodolphe spent 9 years in R&D and M&A at Danisco and DuPont and has been at NC State since 2013. He is also the former Chairman of the Board of Caribou Biosciences, a co-founder of Intellia Therapeutics, Locus Biosciences, and TreeCo.
Rodolphe has been elected into the National Academy of Sciences, the National Academy of Engineering and the National Academy of Inventors.